Opioid Use Disorder Statistics in South Dakota

Comprehensive Opioid Use Disorder statistics for South Dakota, including prevalence, demographics, treatment access, and outcomes data.

3 min read
65%[1]
Treatment Gap for Opioid Use Disorder in South Dakota

Nearly two-thirds of individuals in South Dakota with Opioid Use Disorder (OUD) are not receiving any form of specialty treatment, highlighting a critical gap in care.

2023

Key Takeaways

  • South Dakota's adult Opioid Use Disorder prevalence is 2.7%, which is lower than the national average of approximately 4.0%.2.7%[1]
  • A significant 65% treatment gap exists, meaning nearly two-thirds of South Dakotans with OUD do not receive specialty care.65%[1]
  • American Indian communities face a severe disparity, with an overdose death rate 4.6 times higher than that of White residents.4.6x Higher[2]
  • In 2023, opioids were involved in 47% of the 65 unintentional and undetermined overdose deaths in the state.47%[3]
  • A significant rural-urban divide exists, with OUD prevalence in rural counties (3.1%) being substantially higher than in urban centers (1.8%).3.1% vs 1.8%[4]
  • Access to care is limited, with only 12 mental health providers per 100,000 residents, far below the national average of 21.12 per 100k[5]
  • In 44% of overdose deaths, a potential bystander was present, indicating missed opportunities for life-saving interventions like administering naloxone.44%[6]

An Overview of the Opioid Crisis in South Dakota

Opioid Use Disorder (OUD) remains a significant public health challenge across the United States and within South Dakota. Nationally, an estimated 4.8 million people aged 12 or older experienced OUD in the past year, which translates to a prevalence rate of 1.8% to 2.0% of the adult population[7]. In South Dakota, the crisis is shaped by unique factors including its rural geography, provider shortages, and significant demographic disparities. Understanding the scope of OUD through state-specific data is essential for developing effective prevention, treatment, and harm reduction strategies.

Prevalence of Opioid Use Disorder and Co-Occurring Conditions

While South Dakota's overall OUD prevalence is lower than some national estimates, the data reveals critical areas of concern, particularly the high rates in rural communities. It is also important to view OUD within the broader context of mental health, as substance use disorders frequently co-occur with other conditions. In South Dakota, depression and anxiety are among the most common mental illnesses[5]. Furthermore, the frequent co-occurrence of opioids with stimulants in overdose cases complicates clinical interventions and underscores the polysubstance nature of the current crisis[3].

Geographic Disparities in OUD Prevalence

Adult OUD Prevalence (12-Month)
2.7%
South Dakota
4.0%
United States
South Dakota's rate is 32.5% lower than the national average.
While lower than the national figure, state-level data masks significant internal disparities.
OUD Prevalence within South Dakota
3.1%
Rural Counties
1.8%
Urban Centers
OUD prevalence is 72% higher in rural areas compared to urban centers.
Geographic isolation and limited resources in rural areas are major contributing factors to higher OUD rates.
20.1%[5]
Any Mental Illness (AMI) in SD Adults

The 12-month prevalence of any diagnosable mental illness among adults in South Dakota.

2025
4.7%[5]
Serious Mental Illness (SMI) in SD Adults

The prevalence of mental illnesses that result in serious functional impairment.

2025
51%[3]
Stimulant Involvement in Overdose Deaths

Percentage of unintentional overdose deaths in South Dakota in 2023 that involved a stimulant, often alongside opioids.

2023

Overdose Fatalities and Outcomes

The most tragic outcome of the opioid crisis is the loss of life due to overdose. Between 2020 and 2023, South Dakota recorded 284 overdose deaths[3]. While the state's opioid-specific overdose death rate is roughly 76% lower than the national average, the numbers represent preventable deaths and highlight opportunities for intervention[8]. The state's suicide rate is also a significant concern, exceeding the national average and pointing to broader behavioral health challenges.

Key Overdose Statistics for South Dakota

Opioid Overdose Death Rate

The rate of deaths from opioid overdose among South Dakota residents in 2023.

JAMA Network (2024)
5.7 per 100,000[8]
Total Opioid Overdose Deaths

The number of individuals who died from an opioid-related overdose in 2023.

JAMA Network (2024)
48[8]
Deaths with Intervention Opportunities

In nearly two-thirds of overdose deaths, there was at least one potential opportunity for life-saving intervention.

Letsbeclearsd (2020)
62%[2]

Suicide Rate: South Dakota vs. National Average

Suicide Deaths per 100,000 Population
19.5
South Dakota
14.5
United States
South Dakota's suicide rate is 34.5% higher than the national average.
This elevated rate points to a critical need for accessible mental health services and suicide prevention programs across the state.

Demographic Disparities and At-Risk Populations

The impact of Opioid Use Disorder is not distributed evenly across South Dakota's population. Data reveals profound disparities that highlight systemic inequities and identify specific groups at higher risk. Pronounced disparities among American Indian populations point to long-standing issues related to cultural discrimination and underfunded tribal health services[2]. Additionally, data shows that males and individuals in the 35-44 age group face a disproportionately high risk of overdose fatalities[3]. These statistics are crucial for targeting public health interventions where they are needed most.

Overdose Death Disparities in South Dakota

Overdose Death Rate Ratio
4.6x Higher
American Indian Residents
Baseline
White Residents
American Indians die from overdose at a rate 4.6 times higher than Whites.
This stark disparity reflects systemic inequities in healthcare access and historical trauma.
Share of Overdose Fatalities by Gender
60%
Males
40%
Females
Males account for a majority of overdose deaths in the state.
Targeted outreach and prevention strategies for men may help address this gender gap.

Treatment Gaps and Barriers to Care

Accessing treatment for Opioid Use Disorder in South Dakota is a significant challenge for many residents. The state is designated as a Health Professional Shortage Area (HPSA) for mental health, reflecting a severe lack of providers[5]. While approximately 85% of residents have health insurance covering mental health services, this does not guarantee access, as many still face high out-of-pocket costs and limited availability of specialized care[5]. These structural barriers, combined with the state's rural geography and persistent stigma, contribute to one of the most concerning statistics: the massive gap between those who need treatment and those who receive it.

OUD Treatment Utilization: South Dakota vs. National

Specialty Treatment Rate for OUD
~45%
United States
35%
South Dakota
South Dakota's treatment rate is approximately 22% lower than the national rate.
This gap highlights the state's challenges with treatment capacity and accessibility.
Socioeconomic factors such as income inequality, unemployment, and educational disparities significantly exacerbate mental health and substance use challenges. Persistent stigma also remains a major barrier, preventing many individuals from seeking help due to fear of judgment or discrimination, particularly in smaller, rural communities.

Frequently Asked Questions

Sources & References

All statistics and claims on this page are supported by peer-reviewed research and official government data sources.

1State Unintentional Drug Overdose Reporting System. Doh. Published 2023. Accessed January 2026. https://doh.sd.gov/media/140dz3hm/state-unintentional-drug-overdose-reporting-system-sudors-report-2023.pdf
2Key Substance Use & Overdose Data - Let's Be Clear SD. Letsbeclearsd. Published 2020. Accessed January 2026. https://letsbeclearsd.com/key-data
3Substance Use Data & Reports | South Dakota Department of .... Doh. Accessed January 2026. https://doh.sd.gov/health-data-reports/substance-use-data-reports/(2025)
4SOUTH DAKOTA - National Survey on Drug Use and Health. Substance Abuse and Mental Health Services Administration. Published 2022. Accessed January 2026. https://www.samhsa.gov/data/sites/default/files/reports/rpt56188/2023-nsduh-sae-state-tables_0/2023-nsduh-sae-state-tabs-south-dakota.pdf
5[PDF] SouthDakota 2023 Uniform Reporting System Mental Health Data .... Substance Abuse and Mental Health Services Administration. Accessed January 2026. https://www.samhsa.gov/data/sites/default/files/reports/rpt53148/SouthDakota.pdf
6Executive Summary 2025. Sdbehavioralhealth. Accessed January 2026. https://sdbehavioralhealth.gov/hubfs/2025%20SD%20SEOW%20Executive%20Summary.pdf?hsLang=en
7Opioid Crisis Statistics [2025]: Prescription Opiod Abuse. Drugabusestatistics. Published 2020. Accessed January 2026. https://drugabusestatistics.org/opioid-epidemic/
8Estimates of Illicit Opioid Use in the US | Health Policy - JAMA Network. JAMA Network. Published 2024. Accessed January 2026. https://jamanetwork.com/journals/jama-health-forum/fullarticle/2833721
9CDC Reports Nearly 24% Decline in U.S. Drug Overdose Deaths. Centers for Disease Control and Prevention. Published 2023. Accessed January 2026. https://www.cdc.gov/media/releases/2025/2025-cdc-reports-decline-in-us-drug-overdose-deaths.html