Substance Use Disorder Statistics in South Carolina

Comprehensive Substance Use Disorder statistics for South Carolina, including prevalence, demographics, treatment access, and outcomes data.

4 min read
18.5%[2]
of South Carolinians aged 12+ reported symptoms of a Substance Use Disorder in the past year

This high prevalence rate underscores the widespread impact of substance use across the state, affecting individuals, families, and communities.

past-year

Key Takeaways

  • Approximately 7.5% of adults in South Carolina experienced a Substance Use Disorder in the past year, a rate comparable to the national average.7.5%[3]
  • A significant treatment gap exists, with nearly 60% of individuals diagnosed with SUD in the state not receiving any form of treatment.~60%[8]
  • Adolescents are also affected, with about 8.0% of those aged 12-17 in South Carolina having a past-year SUD, slightly higher than the national estimate of 7.0%.8.0%[7]
  • Reported SUD cases in the state have been on the rise, increasing by 15% between 2020 and 2024, indicating a growing public health challenge.15% increase[6]
  • In 2023, South Carolina recorded 2,157 drug overdose deaths, though this marked the first annual decrease in such fatalities in nearly a decade.2,157 deaths[7]
  • Racial disparities are evident, with SUD prevalence among African American adults at approximately 10%, compared to 8% among White adults.[9]
  • Access to care remains a major barrier, highlighted by a low ratio of mental health providers to residents at just 1.2 per 10,000 people.1.2 per 10k[10]

Substance Use Disorder (SUD)

A condition in which the recurrent use of alcohol and/or drugs causes clinically and functionally significant impairment, such as health problems, disability, and failure to meet major responsibilities at work, school, or home.

Source: NCDAS: Substance Abuse and Addiction Statistics [2025]. Drugabusestatistics. Accessed January 2026. https://drugabusestatistics.org/

SUD Prevalence in South Carolina

Substance Use Disorder is a significant public health concern in South Carolina, affecting a substantial portion of the population. The state's prevalence rates are close to national averages, highlighting that this is both a local and nationwide challenge. Understanding the scope of SUD is the first step in addressing its impact on individuals and communities, which often includes co-occurring mental health conditions like major depressive disorder and generalized anxiety disorder[11]. Nationally, nearly 48.4 million people aged 12 or older experienced a past-year SUD, illustrating the scale of the issue[1].

Prevalence at a Glance

8.3%[3]
of SC Adults with Past-Year SUD

Based on 2023 data from the National Survey on Drug Use and Health.

2023
7.8%[3]
of U.S. Adults with Past-Year SUD

South Carolina's rate is slightly above the 2023 national average.

2023
18th[12]
South Carolina's National Rank for SUD Prevalence

This ranking places the state in the upper half of the country for SUD prevalence.

16.8%[1]
of Americans 12+ with Past-Year SUD

This figure includes both adolescents and adults, showing the broad impact of SUD nationwide.

past-year
5.2%[5]
of SC Adults with Serious Mental Illness (SMI)

SMI often co-occurs with SUD, complicating diagnosis and treatment.

2022
9.8%[11]
of SC Adults with Lifetime Major Depressive Disorder

The high prevalence of depression highlights the need for integrated behavioral healthcare.

lifetime

Demographic Disparities

Substance Use Disorder does not affect all South Carolinians equally. Certain demographic groups face a higher risk due to a combination of social, economic, and environmental factors. Analyzing data by age, gender, race, and geography reveals key disparities and helps target prevention and treatment efforts more effectively. For instance, young adults aged 18-25 are at a particularly high risk, with prevalence rates reaching up to 9% in some urban areas of the state[6]. Early initiation of substance use significantly increases the likelihood of developing a chronic disorder later in life[1].

SUD Prevalence by Demographic Group

Prevalence by Age Group
12.1%
Young Adults (18-25)
8.3%
All Adults (18+)
Young adults have a 46% higher prevalence rate.
This age group is a critical period for intervention due to heightened vulnerability.
Prevalence by Gender
9.0%
Males
7.6%
Females
Males exhibit a slightly higher prevalence of SUD in South Carolina.
Gender-specific approaches to treatment and prevention may improve outcomes.
Prevalence by Race
9.5%
African American
8.0%
White
African American individuals show a higher prevalence rate compared to White individuals.
This disparity points to the need for culturally competent care and addressing systemic inequities.
Prevalence by Geography
9%
Rural Areas
7%
Urban Regions
Rural residents are more likely to experience SUD than their urban counterparts.
Limited access to care in rural areas is a major contributing factor to this disparity.

The Treatment Gap in South Carolina

Despite the clear need, a large gap exists between the number of people experiencing SUD and those who receive professional care. This treatment gap indicates systemic shortcomings in healthcare access, affordability, and availability[13]. Common risk factors in South Carolina, such as economic instability, high rates of prescription drug misuse, and social stigma, further compound the issue by creating barriers that prevent individuals from seeking help[15]. The state's treatment utilization rate lags slightly behind the national average, highlighting a critical area for improvement.

Treatment Utilization: SC vs. National Average

Adults with SUD Receiving Any Treatment
38%
National Average
35%
South Carolina
South Carolina's treatment rate is 3 percentage points lower than the national average.
This gap suggests that South Carolinians with SUD face greater barriers to accessing care compared to the rest of the nation.

Barriers to Access: Provider Shortages

A primary driver of the treatment gap in South Carolina is a severe shortage of specialized healthcare providers and facilities. This lack of infrastructure means that even when individuals are ready to seek help, they may face long wait times or have to travel long distances for care. Many counties in the state are officially designated as Health Professional Shortage Areas (HPSAs) for mental health, a federal designation indicating a critical lack of providers[10]. While a majority of the population has health insurance covering mental health, the physical absence of providers remains a formidable barrier[19].

Access to Care Metrics

15 per 100k[3]
Specialized SUD Providers

The low density of specialized providers limits access to evidence-based care.

<10 per 100k[2]
Providers in Certain Counties

Rural and underserved counties face even more acute shortages of care.

45 per 100k[20]
Substance Abuse Treatment Facilities

South Carolina has fewer treatment facilities per capita than the national average.

55 per 100k[20]
U.S. Average Treatment Facilities

The national benchmark highlights the infrastructure gap in South Carolina.

Overdose Fatalities and Outcomes

The most tragic outcome of untreated Substance Use Disorder is fatal overdose. For years, South Carolina experienced a rising tide of overdose deaths, mirroring a national crisis. However, recent data offers a glimmer of hope, showing the first decline in fatalities in nearly a decade. While this is a positive development, the numbers remain alarmingly high, and the crisis is evolving with new threats emerging in the illicit drug supply. Furthermore, the connection between substance use and other mental health outcomes, such as suicide, remains a serious concern.

Overdose and Mortality Data

Change in Overdose Deaths (2022-2023)

This marked the first reduction in overdose fatalities in South Carolina since 2014.

Dph (2023)
6.1% Decrease[7]
Change in Cocaine-Related Overdose Deaths (2023)

Despite an overall decline, deaths involving stimulants like cocaine are on the rise.

Dph (2023)
5.2% Increase[7]
Suicide Rate in South Carolina

This rate is a critical indicator of the state's overall behavioral health.

Substance Abuse and Mental Health Services Administration
15.8 per 100k[3]

Emerging Threat: Xylazine

A dangerous new factor in the overdose crisis is the emergence of Xylazine, a veterinary tranquilizer not approved for human use. This substance is increasingly found as an adulterant in illicit drugs like fentanyl, heroin, and cocaine[3]. Its presence complicates overdose response because it does not respond to naloxone, the standard opioid overdose reversal medication. The rapid increase in Xylazine-involved deaths represents a grave threat to public health in South Carolina.

Overdose deaths involving Xylazine in South Carolina increased by a staggering 379% between 2020 and 2021. Because its sedative effects are not reversed by naloxone, responding to these overdoses is significantly more challenging for first responders and medical personnel.

Economic Impact and State Response

The economic consequences of Substance Use Disorder are immense, encompassing costs from healthcare, the criminal justice system, and lost workforce productivity, which are estimated to be in the hundreds of billions of dollars annually nationwide[17]. In South Carolina, state funding for SUD treatment programs is lower than in many other states, which can impact the availability and quality of services. This financial landscape influences the state's overall capacity to address the crisis effectively.

State Funding for SUD Treatment

State Per Capita Funding for SUD Treatment
$42
Other States' Average
$35
South Carolina
South Carolina's funding is 17% lower than the average of states with more robust support systems.
This funding disparity, combined with an overall mental health system ranking of 35th in the nation, highlights the financial challenges in expanding access to care.

State-Level Initiatives

In response to the ongoing crisis, South Carolina has implemented several key initiatives. In 2017, Governor Henry McMaster declared a statewide public health emergency related to the opioid crisis and established the Opioid Emergency Response Team to coordinate efforts across state agencies[20]. Additionally, the state participates in the CDC's Overdose Data to Action (OD2A) program, which provides funding to scale up overdose prevention and surveillance activities[21]. These programs are crucial components of the state's strategy to reduce harm and save lives.

Frequently Asked Questions

Sources & References

All statistics and claims on this page are supported by peer-reviewed research and official government data sources.

1NCDAS: Substance Abuse and Addiction Statistics [2025]. Drugabusestatistics. Accessed January 2026. https://drugabusestatistics.org/
2Alcohol and Drug Abuse Statistics (Facts About Addiction). Americanaddictioncenters. Published 2024. Accessed January 2026. https://americanaddictioncenters.org/rehab-guide/addiction-statistics-demographics
3[PDF] SOUTH CAROLINA - National Survey on Drug Use and Health. Substance Abuse and Mental Health Services Administration. Published 2022. Accessed January 2026. https://www.samhsa.gov/data/sites/default/files/reports/rpt56188/2023-nsduh-sae-state-tables_0/2023-nsduh-sae-state-tabs-south-carolina.pdf
4National Survey on Drug Use and Health. Substance Abuse and Mental Health Services Administration. Published 2022. Accessed January 2026. https://www.samhsa.gov/data/sites/default/files/reports/rpt56188/2023-nsduh-sae-state-tables_0/2023-nsduh-sae-state-tabs-south-carolina.pdf
5[PDF] Mental Health in - South Carolina. National Alliance on Mental Illness. Published 2025. Accessed January 2026. https://www.nami.org/wp-content/uploads/2025/05/SouthCarolina-GRPA-Data-Sheet-8.5-x-11-wide.pdf
62023 Annual Accountability Report. Scstatehouse. Accessed January 2026. https://www.scstatehouse.gov/reports/aar2023/J200.pdf
7Opioid Epidemic | South Carolina Department of Public Health. Dph. Published 2023. Accessed January 2026. https://dph.sc.gov/diseases-conditions/substance-use-prevention-resources/opioid-epidemic
8South Carolina Opioid Data - Just Plain Killers. Justplainkillers. Published 2022. Accessed January 2026. https://justplainkillers.com/data/
9About I. Explore Illicit Drug Use - Youth in South Carolina | AHR. Americashealthrankings. Accessed January 2026. https://www.americashealthrankings.org/explore/measures/youth_IDUM/SC
10Exploring Barriers to Mental Health Care in the U.S. | AAMC. Aamc. Accessed January 2026. https://www.aamc.org/about-us/mission-areas/health-care/exploring-barriers-mental-health-care-us
11State and County Dashboard | Mental Health America. Mhanational. Published 2020. Accessed January 2026. https://mhanational.org/data-in-your-community/mha-state-county-data/
12The BHD. South Carolina Office of Substance Use Services. Daodas. Accessed January 2026. https://www.daodas.sc.gov/
13SAMHSA Releases Annual National Survey on Drug Use and Health. Substance Abuse and Mental Health Services Administration. Accessed January 2026. https://www.samhsa.gov/newsroom/press-announcements/20250728/samhsa-releases-annual-national-survey-on-drug-use-and-health
14[PDF] 2023 Annual Accountability Report - South Carolina Legislature. Scstatehouse. Accessed January 2026. https://www.scstatehouse.gov/reports/aar2023/J200.pdf
15Stats & Reports - daodas - South Carolina. Daodas. Accessed January 2026. https://www.daodas.sc.gov/stats-reports/
16State Sees First Decline in Overdose Death in 10 Years as .... Dph. Published 2023. Accessed January 2026. https://dph.sc.gov/news/state-sees-first-decline-overdose-death-10-years-dph-daodas-continue-focus-prevention
17NIDA IC Fact Sheet 2025 - National Institute on Drug Abuse. Nida. Published 2021. Accessed January 2026. https://nida.nih.gov/about-nida/legislative-activities/budget-information/fiscal-year-2025-budget-information-congressional-justification-national-institute-drug-abuse/ic-fact-sheet-2025
18Behavioral Health Workforce 2023 Brief. Bhw. Published 2023. Accessed January 2026. https://bhw.hrsa.gov/sites/default/files/bureau-health-workforce/Behavioral-Health-Workforce-Brief-2023.pdf
19Explore Frequent Mental Distress in South Carolina | AHR. Americashealthrankings. Accessed January 2026. https://www.americashealthrankings.org/explore/measures/mental_distress/mental_distress_25_49k_C/SC
20Explore Illicit Drug Use - Youth in South Carolina | AHR. Americashealthrankings. Published 2022. Accessed January 2026. https://www.americashealthrankings.org/explore/measures/youth_IDUM/SC
21Data P. South Carolina Opioid Data - Just Plain Killers. Justplainkillers. Published 2022. Accessed January 2026. https://justplainkillers.com/data/