Opioid Use Disorder Statistics in Colorado

    Comprehensive Opioid Use Disorder statistics for Colorado, including prevalence, demographics, treatment access, and outcomes data.

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    Nearly 60%[1]
    of individuals with Opioid Use Disorder in Colorado do not receive any form of treatment

    This significant treatment gap highlights the barriers many face in accessing necessary care, including stigma, cost, and lack of available services.

    2023

    Key Takeaways

    • An estimated 3.5% of adults in Colorado meet the criteria for Opioid Use Disorder, a figure that underscores the significant public health challenge facing the state.3.5%[2]
    • A substantial treatment gap exists, with less than half (45%) of Coloradans diagnosed with OUD accessing evidence-based treatment services.45%[2]
    • Young adults aged 18-25 are a particularly vulnerable group, with an OUD prevalence rate of 5.2%, significantly higher than other adult age groups.5.2%[2]
    • Geographic disparities are evident, as rural counties in Colorado report a higher OUD prevalence of 4.0% compared to 3.2% in urban centers.4.0%[3]
    • The state's drug overdose death rate was 21.6 per 100,000 residents between 2020 and 2024, reflecting the severe consequences of the opioid crisis.21.6 per 100k[4]
    • Access to care remains a major hurdle, with 2.9 million Coloradans living in designated Mental Health Professional Shortage Areas.2.9 Million[5]
    • The crisis is worsening, with a 12% increase in Opioid Use Disorder diagnoses observed in Colorado between 2020 and 2023.12% increase[2]

    The Scope of the Opioid Crisis in Colorado

    Opioid Use Disorder (OUD) represents a significant and growing public health crisis in Colorado. The state has one of the highest prevalences of mental illness in the nation, and substance use disorders are a major component of this challenge[6]. Understanding the prevalence of OUD is the first step in grasping the scale of the issue and developing effective interventions. The following statistics provide a snapshot of how many Coloradans are affected by OUD and related mental health conditions.

    2.8%[7]
    Adult OUD Prevalence (2022)

    This rate was higher than the national average of 2.3% for the same period.

    2022
    15th[1]
    National Rank for OUD Burden

    A SAMHSA report places Colorado among the top third of states for the overall burden of Opioid Use Disorder.

    2023
    21%[8]
    Adults with Any Mental Illness

    Nearly one in five adults in Colorado exhibit symptoms of a diagnosable mental disorder, which can co-occur with OUD.

    2022

    Opioid Use Disorder (OUD)

    Opioid Use Disorder is a problematic pattern of opioid use leading to clinically significant impairment or distress. It is a medical condition characterized by an inability to consistently abstain, impairment in behavioral control, craving, diminished recognition of significant problems with one’s behaviors and interpersonal relationships, and a dysfunctional emotional response.

    Source: Opioid Use Disorder - Psychiatry.org. American Psychiatric Association. Published 2023. Accessed January 2026. https://www.psychiatry.org/patients-families/opioid-use-disorder

    Demographics and Disparities

    Opioid Use Disorder does not affect all Coloradans equally. Significant disparities exist across different age groups, geographic locations, and genders. Younger adults, for instance, face a disproportionately high risk, and those living in rural areas often encounter different challenges and prevalence rates than their urban counterparts. Examining these demographic breakdowns is crucial for targeting resources and prevention efforts where they are needed most.

    OUD Prevalence by Age Group
    5.2%
    Young Adults (18-25)
    3.0%
    Adults (26-64)
    Young adults have a 73% higher prevalence rate
    Early adulthood is a particularly vulnerable period for the onset of OUD, highlighting the need for early intervention and targeted support for this age group.
    OUD Prevalence by Geography
    4.0%
    Rural Counties
    3.2%
    Urban Areas
    Rural prevalence is 25% higher than in urban areas
    Higher rates in rural areas may be linked to factors like limited economic opportunities, provider shortages, and unique social dynamics.
    Gender Distribution of OUD Diagnoses
    60%
    Male
    40%
    Female
    Men account for a larger share of diagnosed OUD cases
    While men are more frequently diagnosed, both genders face significant risks. Males in the 25-44 age group are noted as being disproportionately affected.

    Treatment Landscape and Barriers to Access

    Despite having a higher-than-average number of treatment facilities, a significant portion of Coloradans with OUD do not receive care. Barriers such as insurance limitations, a shortage of specialized providers in many areas, and the stigma surrounding addiction prevent people from seeking help[9]. The data reveals a complex picture where resources exist but are not always accessible to those who need them most, especially in rural communities.

    OUD Treatment Rate via Medicaid

    Colorado's rate is notably higher than the national average of 37%, suggesting state programs are having some success.

    Coloradoseow (2023)
    45%[2]
    Treatment Facilities in Colorado

    This is slightly above the national average of 12 facilities per 100,000 residents.

    Coloradoseow (2020)
    15 per 100,000[1]
    Provider Density in Some Rural Regions

    This stark provider shortage highlights the geographic disparity in access to mental health and addiction services.

    National Alliance on Mental Illness (2025)
    1 per 20,000[5]

    Overdose Mortality and Health Outcomes

    The most tragic consequence of the opioid crisis is the loss of life due to overdose. Colorado has seen a devastating number of deaths, with the nature of the crisis evolving due to the increased presence of potent synthetic opioids like fentanyl[4]. While long-term trends have shown a frightening increase in mortality, recent data offers a glimmer of hope, suggesting that prevention and treatment efforts may be starting to bend the curve.

    State Response and Economic Investment

    Addressing the opioid crisis requires substantial financial investment and strategic policy initiatives. Colorado has allocated significant funding toward its behavioral health infrastructure and specific programs aimed at increasing access to Medication-Assisted Treatment (MAT)[1]. These efforts are critical, as the economic toll of OUD—related to healthcare costs, lost productivity, and criminal justice involvement—is enormous[10]. The following data points illustrate the scale of the state's financial commitment to combating this crisis.

    $8.5 Billion[11]
    Projected Behavioral Health Spending

    This is the estimated investment in Colorado's behavioral health system between fiscal years 2022 and 2025.

    FY 2022-2025
    $67.67[11]
    Per Capita Mental Health Spending

    This spending level places Colorado 27th among states, indicating a mid-range investment compared to peers.

    FY 2024
    25% Increase[9]
    in Treatment Uptake via Medicaid

    Following the 2020 expansion of Medicaid coverage for OUD treatment, uptake among beneficiaries rose significantly.

    Post-2020
    It is important to note that statistical comparisons over time can be complex. Changes in diagnostic criteria, such as the shift from DSM-IV to DSM-5, have been shown to yield a 1.6 to 2.6-fold higher prevalence of substance use disorders. Additionally, recent updates to Census data collection methods for race and ethnicity may affect long-term trend analysis for specific demographic groups.

    Frequently Asked Questions

    Sources & References

    All statistics and claims on this page are supported by peer-reviewed research and official government data sources.

    12023 Opioids Profile - Colorado SEOW. Coloradoseow. Published 2020. Accessed January 2026. https://www.coloradoseow.org/project/2023-opioids-profile/
    2[PDF] View 2023 Opioids Profile - Colorado SEOW. Coloradoseow. Published 2023. Accessed January 2026. https://www.coloradoseow.org/wp-content/uploads/2023/05/2023-Opioids-Profile.pdf
    3The Problem - Take Meds Seriously. Takemedsseriously. Published 2023. Accessed January 2026. https://takemedsseriously.org/the-problem/
    4The N. Colorado drug overdose statistics. Cdphe. Accessed January 2026. https://cdphe.colorado.gov/registries-and-vital-statistics/state-unintentional-drug-overdose-reporting-system-sudors/colorado
    5[PDF] Mental Health in - Colorado. National Alliance on Mental Illness. Published 2025. Accessed January 2026. https://www.nami.org/wp-content/uploads/2025/05/Colorado-GRPA-Data-Sheet-8.5-x-11-wide.pdf
    6Where Does Colorado Rank for Mental Health: 2025 Update. Axismh. Published 2025. Accessed January 2026. https://axismh.com/where-does-colorado-rank-for-mental-health-2025-update/
    7[PDF] Colorado Opioid Summary - National Institute on Drug Abuse. Nida. Published 2016. Accessed January 2026. https://nida.nih.gov/sites/default/files/21949-colorado-opioid-summary.pdf
    8Mental health data | Behavioral Health Administration. Bha. Published 2022. Accessed January 2026. https://bha.colorado.gov/data-and-reports/performance-hub/mental-health-data
    9Opioid Crisis Statistics [2025]: Prescription Opiod Abuse. Drugabusestatistics. Accessed January 2026. https://drugabusestatistics.org/opioid-epidemic/
    10Opioid Facts and Statistics | HHS.gov. Hhs. Published 1999. Accessed January 2026. https://www.hhs.gov/opioids/statistics/index.html
    11New report: Colorado remains in mental health crisis. Coloradopolitics. Published 2025. Accessed January 2026. https://www.coloradopolitics.com/2025/10/01/new-report-colorado-remains-in-mental-health-crisis/