This equates to approximately 48.5 million people, highlighting the widespread impact of substance use disorders across the nation.
Key Takeaways
- Substance Use Disorder (SUD) affects 48.5 million people aged 12 or older in the U.S., representing a significant public health crisis.17.1%[5]
- A significant treatment gap persists, with roughly 8 out of 10 people who need SUD treatment not receiving it.75-85%[7]
- The total societal cost of substance use in the U.S. exceeds $740 billion annually, including healthcare, criminal justice, and lost productivity.>$740 Billion[8]
- Individuals with an SUD have a suicide mortality risk that is approximately 5.6 times higher than that of the general population.5.6x Higher[8]
- Young adults aged 18-25 face the highest risk, with a past-year SUD prevalence rate of approximately 16%.16%[5]
- The drug overdose crisis continues to escalate, with over 1.15 million deaths recorded in the United States since 1999.>1.15 Million[2]
- Co-occurring disorders are common, with about 10% of adults experiencing both a mental health issue and a substance use disorder simultaneously.10%[9]
Understanding the Scale of Substance Use in America
Substance Use Disorder (SUD) is a significant public health issue in the United States, affecting millions of individuals and families across all demographics. The condition involves the recurrent use of alcohol and/or drugs causing clinically significant impairment, including health problems, disability, and failure to meet major responsibilities at work, school, or home. According to the most recent National Survey on Drug Use and Health (NSDUH), 59.0% of people aged 12 or older reported using at least one substance in the past month[5]. Understanding the prevalence and scope of SUD is the first step toward addressing its profound impact on individuals and society.
Substance Use Disorder (SUD)
Source: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. American Psychiatric Publishing; 2013.
Prevalence statistics help quantify the scope of SUD, distinguishing between those who have ever had the disorder and those with an active condition. Lifetime prevalence captures anyone who has ever met the diagnostic criteria, offering insight into the total community burden[11]. In contrast, 12-month prevalence identifies current cases, reflecting the immediate demand for healthcare services[12]. The difference between these figures highlights the episodic nature of SUD, where many individuals achieve remission over time.
National Prevalence of SUD and Substance Use
Indicates the proportion of adults who have ever met the criteria for an SUD in their lives.
Represents the percentage of adults with an active SUD within the last 12 months.
Highlights alcohol as one of the most common substances involved in SUDs.
Includes disorders related to illicit drugs and the misuse of prescription medications.
Nearly one-third of adults experienced either a mental illness or a substance use disorder in the past year.
This highlights the commonality of polysubstance use among individuals with SUD.
Demographics and Disparities
Substance Use Disorder does not affect all populations equally. Significant disparities exist across age, gender, race, ethnicity, sexual orientation, and socioeconomic status. Understanding these differences is crucial for developing targeted prevention strategies and equitable treatment solutions. For example, young adulthood is a period of heightened vulnerability, while certain minority groups face a disproportionate burden of negative outcomes despite having similar or lower prevalence rates.
Gender, sexual orientation, and race also play significant roles in the prevalence and experience of SUD. While men are more likely to develop an SUD, women often face greater stigmatization and barriers to treatment[25]. LGBTQ+ individuals experience SUD at nearly double the rate of their heterosexual and cisgender peers, often linked to stressors like discrimination and family rejection[8].
Disparities in SUD Prevalence
The Treatment Gap and Barriers to Care
Despite the high prevalence of Substance Use Disorder, a vast majority of individuals who need help do not receive it. This "treatment gap" is one of the most significant challenges in public health. Data consistently shows that fewer than one in five people with a diagnosed SUD receive any form of specialty treatment[13]. The reasons for this gap are complex, ranging from systemic barriers like cost and lack of available care to personal factors like stigma and denial.
The Overwhelming Gap in Treatment
Despite 54.2 million Americans needing care, the vast majority go untreated.
Stigma remains a primary reason why individuals do not seek help for SUD.
Long delays in seeking care can lead to more severe health and social consequences.
This highlights a critical treatment gap in a high-risk population.
Economic Impact of Substance Use Disorders
The economic consequences of untreated substance use are staggering. These costs are not limited to direct healthcare expenses but also include significant losses in workplace productivity, increased involvement with the criminal justice system, and social welfare costs. Quantifying this economic burden underscores the value of investing in prevention and treatment, as effective interventions can generate substantial savings for society.
The Financial Toll of SUD
This includes costs from absenteeism, presenteeism (working while impaired), and inability to work.
This comprehensive figure includes both healthcare costs and lost productivity.
Outcomes, Recovery, and Hope
Despite the challenges, recovery from Substance Use Disorder is not only possible but common. However, SUD is a chronic condition, and relapse can be part of the recovery process, with rates similar to other chronic illnesses like hypertension or asthma[32]. Effective, evidence-based treatments significantly improve outcomes, reduce mortality, and help individuals regain control of their lives.
Effectiveness of Treatment
Medication-Assisted Treatment (MAT) is a highly effective intervention for opioid use disorder.
Nih (2023)Integrating pharmacotherapy with psychotherapy is more effective than either approach alone.
Nih (2023)Long-term recovery significantly reduces the risk of relapse, highlighting the importance of sustained support.
Pew (2025)Trends in Substance Use and Treatment
The landscape of substance use and treatment is constantly evolving. Over the past decade, the need for SUD treatment has risen dramatically, driven by factors like the opioid crisis and the stressors of the COVID-19 pandemic. While challenges remain, the rapid expansion of telehealth has created new avenues for accessing care, fundamentally changing how treatment is delivered.
The COVID-19 pandemic significantly impacted SUD prevalence and treatment. Stressors from lockdowns and economic uncertainty led to an increase in substance use, with prevalence rates reaching 12% among adults during the peak of the pandemic[34]. Simultaneously, disruptions to in-person services caused treatment utilization to fall, though the expansion of telehealth provided a critical lifeline for many[8].
Impact of the COVID-19 Pandemic on SUD Prevalence
Frequently Asked Questions
Sources & References
All statistics and claims on this page are supported by peer-reviewed research and official government data sources.
